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This collection of essays on the lung summarizes many established opinions, and the interesting group discussions touch on several exciting hypotheses and yet hardly any concepts on aging of the lung can be considered established. Aging in general is not well understood and information on how the lung grows old is very sparse indeed. However, valuable material on pulmonary function and structure is contained in these pages.
The tremendous drop with age in the maximal breathing capacity remains obscure, but Dubois presents data on a few old lungs which helps to explain it. The aging process limits the lateral separation of collagen subunits and increases the elastin content of lungs; yet old lungs have less recoil than young ones. Radford says he does not know about aged surfactant but is most provocative in his thoughts about the high residual volume in old age. Robinson summarizes the data on the impaired
Filley GF. Aging of the Lung: Perspectives. The Tenth Hahnemann Symposium. JAMA. 1965;192(8):730. doi:10.1001/jama.1965.03080210074038