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Article
May 31, 1965

Late Intestinal Complications of Cystic Fibrosis

Author Affiliations

From the Pediatric Metabolism Branch of the National Institute of Arthritis and Metabolic Disease (Drs. Talamo and di Sant'Agnese), and the Surgery Branch, National Cancer Institute (Dr. Mullins), National Institutes of Health, Bethesda, Md.

JAMA. 1965;192(9):741-746. doi:10.1001/jama.1965.03080220005001
Abstract

Regardless of age, all patients with cystic fibrosis are subject to intestinal complications due to the abnormal character of their fecal contents. Five cases were studied. The patients ages ranged from 13 months to 31 years. Two patients had fecal masses, one with and the other without evidence of intestinal obstruction, and both responded to medical measures. In three surgical problems developed: ileocolic intussusception, small bowel volvulus, and obturation unresponsive to conservative management. Guiding principles for medical and surgical management are outlined, based on our own experiences and a review of 23 cases from the literature.

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