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May 31, 1965

Cadaveric Renal Homotransplantation With Inadvertent Transplantation of Carcinoma

Author Affiliations

From the departments of surgery, urology, medicine, and pathology, University of California Center for the Health Sciences, and Wadsworth Hospital, Veterans Administration Center, Los Angeles.

JAMA. 1965;192(9):752-754. doi:10.1001/jama.1965.03080220016003

The recipient of a cadaver renal transplant survived five months with satisfactory renal function. The donor of the graft died from a bronchogenic carcinoma. There was no gross evidence of metastasis in the kidney at the time of nephrectomy in the donor. Four months after transplantation, malignant cells were seen in a biopsy of the grafted organ. This tumor was histopathologically identical to that in the donor. The recipient died from widespread metastasis of transplanted cancer five months following renal grafting.