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To the Editor:—
Androgens have been, at least those "strong" ones, thought responsible for the growth of hair on the face and head of man and indeed, likewise, indicted for the bald top. To add more confusion I hereby submit the case history of a man proven to have prostatic cancer, and who, though he had been bald for many years, began to notice the "return" of hair during "estrogen" therapy after orchiectomies.A 58-year-old man with proven carcinoma of the prostate was first seen in October 1961. Bilateral orchiectomies were performed followed by a ten-day course of diethylstilbestrol (stilbestrol), 1 gm given intravenously daily. He was discharged and told to take chlorotrinisene, 12 mg daily. In March 1962, the chlorotrinisene was discontinued and diethylstilbestrol 5 mg three times daily was given. In December 1962, severe bone pain responded to another 14-day course of diethylstilbestrol. At this time noticeable new
Bunge RG. These Hairs Now Blossom Whiter than the Swan. JAMA. 1965;192(9):786-787. doi:10.1001/jama.1965.03080220050025