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Article
October 18, 1965

Jaundice and Congenital Hypothyroidism

Author Affiliations

From the departments of pediatrics, Olean Medical Group, and St. Francis Hospital, Olean, NY.

JAMA. 1965;194(3):299-300. doi:10.1001/jama.1965.03090160077027
Abstract

THE HIGH INCIDENCE of prolonged neonatal jaundice in infants with congenital hypothyroidism, documented by Aakerren1 and confirmed by Christensen,2 requires reemphasis. Since jaundice may be the first sign of congenital hypothyroidism,3 this possibility must be kept in mind in the investigation of any case of jaundice in infancy. Only by maintaining a high index of suspicion will such infants be recognized early enough to enhance the possibility for normal mental as well as physical development. The following case emphasizes this fact.

Report of a Case  This female infant was delivered by low forceps at term. The mother, aged 20 years, had a pregnancy complicated by pyelitis which responded promptly to nitrofurantoin (Furadantin). At birth the infant weighed 8 lb 1/4 oz (3,636 gm), was 19 1/2 inches (49.5 cm) long, and had no abnormalities on initial examination. During her stay in the nursery no jaundice was noted,

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