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November 22, 1965

New Epidemiologic Study Suggests Possible Family Cancer Patterns

JAMA. 1965;194(8):19-20. doi:10.1001/jama.1965.03090210117062

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A new epidemiologic study indicates occurrence of breast cancer among women whose mothers had the same disease may be significantly greater than expected.

The conclusion is based on a preliminary report of a study of the offspring of 436 mothers who later developed breast cancer and 490 mothers who later developed genital cancer.

The study also indicated:

  • Deaths among the offspring of all the mothers with cancer was significantly greater than expected, with some indication that the children of the women with genital cancer had a higher mortality risk.

  • Risk of babies born of women who later developed genital cancer dying within the first month of life (0.0546) was approximately twice as great as that of babies born of women who later developed breast cancer (0.0246).

  • Both sons and daughters of mothers with later genital cancer had a significantly greater risk of developing leukemia than expected. A

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