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November 29, 1965

Experimental Atherosclerosis

Author Affiliations

Madison, Wis


by Paris Constantinides, 91 pp, 103 illus, $11.50, Amsterdam and New York: Elsevier Publishing Co., 1965.

JAMA. 1965;194(9):1026. doi:10.1001/jama.1965.03090220082040

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In this relatively small book, the author makes a surprisingly complete presentation of the experimental evidence dealing with the factors that produce atherosclerosis, chiefly in the rabbit. Those factors which he discusses at length are lipemia, arterial injury, and thrombosis. The presentation is oriented largely to the morphology of the lesions, but at the same time the chemical and physiological aspects are not neglected. The volume also contains short sections which deal with human atherosclerosis, the care of laboratory animals, and some unsolved problems in atherosclerosis research. The writing is quite good—direct, clear, and at times even entertaining. The reader gathers the impression not only that the author knows a great deal about this field but also that he judges fairly the relative merits of the frequently conflicting bits of evidence. There are numerous references and a sizable number of figures and illustrations which vary considerably in quality.

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