December 20, 1965


JAMA. 1965;194(12):1318. doi:10.1001/jama.1965.03090250052019

Palmar keratoses are observed in a large portion of the patients with cancer. A communication in a recent issue of the Archives of Dermatology surveys 671 patients with proved cancers in whom palmar keratoses were found in 46% of the men and 26% of the women.1 In a control group of 685 persons without cancer, palmar keratoses were seen in only 12% of the men and 5% of the women. The prevalence of these keratoses varied with age in both groups, reaching a peak during the seventh decade. However, in each age group, keratoses always occurred more frequently in patients with cancer. The palmar lesions were observed with similar frequency in all types of cancer. For example, palmar lesions were found in 54% of the men with cancer of the skin, 45% with cancer of the lung, and 44% with cancer of the colon. Keratoses were present in 29%

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