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January 31, 1966

Vaccination Against Measles in the Canadian Arctic

Author Affiliations

From the Virus Laboratories, Department of National Health and Welfare, Ottawa (Dr. Furesz) and Frobisher Bay General Hospital, Frobisher Bay, Northwest Territories, Canada (Dr. Habgood).

JAMA. 1966;195(5):342-344. doi:10.1001/jama.1966.03100050050017

Measles virus vaccine, live, attenuated (Schwarz strain), was administered in June 1965 to 84 Eskimo and 21 white children, 7 months to 6 years of age, living in a village of the Canadian Eastern Arctic. Specific antibodies to measles virus were detected in 100% of 42 serum specimens from the Eskimo children and 15 (94%) of 16 serum specimens from the white children. Except for high fever, severe clinical reactions were not observed during the vaccination program. Rectal temperatures over 103 F (39.4 C) were noted in 12 (33.3%) of 36 Eskimo children and in 3 (18.8%) of 16 white children 6 to 11 days following vaccination. Mild rash developed in 11 (30.6%) of 36 Eskimo and in 6 (37.5%) of 16 white children. These data have demonstrated the safety and efficacy of use of the Schwarz vaccine among Eskimo children.