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Article
February 21, 1966

SIMULATION OF DIABETES

JAMA. 1966;195(8):681. doi:10.1001/jama.1966.03100080121040
Abstract

Greater awareness of diabetes mellitus by both physicians and patients, plus the easy availability of office techniques for testing urine sugar, has resulted in earlier diagnosis of the condition. However, pediatricians now encounter the problem of false-positive diagnoses of diabetes. A communication in a recent issue of the American Journal of the Diseases of Children describes three patients with suspect diagnoses of diabetes mellitus1. These children were initially seen by their physician for symptoms of an upper-respiratory-tract infection. Antibiotics and symptomatic therapy were prescribed, and after several days the patients were seen once again because of persistence or worsening of the original complaints. At that time, a routine urinalysis disclosed the presence of glucose and acetone in the urine.

Subsequent blood-glucose determinations ranged from moderately elevated (144 mg/100 ml) to markedly elevated (235 mg/100 ml). Despite these positive laboratory findings, the diagnosis of diabetes mellitus was questioned because symptoms

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