February 21, 1966

Cerebral Edema

Author Affiliations

Los Angeles


by Louis Bakay and Joseph C. Lee, 192 pp, 58 illus, $9.75, Springfield, Ill: Charles C Thomas, Publisher, 1965.

JAMA. 1966;195(8):706. doi:10.1001/jama.1966.03100080146070

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In a definitive and well-produced work, the authors bring up to date the mass of experimental evidence and clinical observation relating to the cerebral edemas (cerebral swelling). The authors discuss the present status of our knowledge of the fluid content of the brain and its solute, and the anatomical and physiological substrate of the blood-brain barrier which plays a role in certain forms of cerebral edema. The major emphasis of the monograph is a compilation of information gained from laboratory studies of various experimental brain edemas. In this sifting of many contributions, including substantive ones of their own, the authors have analyzed in a reasonably critical way, the validity and shortcomings of the experimental techniques. The pathophysiology of the human cerebral edemas and their clinical diagnosis is given thorough treatment. Due to the method of presentation, however, the reader must be alert not to confuse that which is related and

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