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March 28, 1966

Lung Cancer: New Circulation Concept

JAMA. 1966;195(13):38. doi:10.1001/jama.1966.03100130024010

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A Canadian radiologist asserts that most metastatic invasions of the lung are supplied primarily by the pulmonary circulation, rather than by the bronchial system as is commonly thought.

Based upon a study of more than 30 lungs of patients who succumbed to cancers, Eric N. Campbell Milne, MD, London, Ontario, disputed the concept that primary and secondary cancers of the lung have a similar circulation. He presented his findings to the 1966 convention of the Canadian Association of Radiologists at Montreal.

'Far From Academic'  "The question of the vascular supply to these tumors is far from being an academic one. If secondary deposits within the lung have a pulmonary circulation, they can be readily perfused by cytotoxic drugs," he said."It should also be possible on the basis of the different types of circulation to distinguish between a primary lesion or a metastasis on the basis of bronchial or selective

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