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May 16, 1966

Chronic Lymph Dialysis in Renal Failure

JAMA. 1966;196(7):33-34. doi:10.1001/jama.1966.03100200015004

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Extracorporeal lymph dialysis appears to be a promising technique for the maintenance of patients in chronic renal failure, investigators at the University of Texas Medical Branch, Galveston, report.

These investigators, Harry Sarles, MD, Garland Smith, Jr., MD, Jay C. Fish, MD, Curtis P. Artz, MD, August R. Remmers, Jr., MD, and Thomas S. Hargest, have made clinical trials with lymph dialysis in five patients over the past 18 months.

"The properties of the lymphatic system are quite well suited to a dialysis program," Dr. Sarles told the annual meeting in Atlantic City of the American Society for Artificial Internal Organs. "The dialysis and reinfusion of lymph has provided rather striking clinical improvement in patients with chronic renal failure and somewhat less striking chemical improvement."

Moreover, studies of the effect of thoracic duct drainage upon lymphocytic homeostasis indicate the technique may be useful in maintaining immunotolerance of organ transplants.

The technique

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