June 27, 1966


Author Affiliations

Washington, DC


by Vincent Marks and F. Clifford Rose, 356 pp, 11 illus, $12, Oxford: Blackwell Scientific Publications, Ltd. (Philadelphia: F. A. Davis Co.), 1965.

JAMA. 1966;196(13):1163. doi:10.1001/jama.1966.03100260101050

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This book sets out to summarize contemporary knowledge concerning hypoglycemic syndromes in man. The causes of spontaneous hypoglycemia other than organic hyperinsulinism, are not widely known, yet none can be neglected if chronic ill health and, at times, disaster are to be avoided.

The book starts with a clear and concise presentation of the many factors involved in the maintenance of the blood sugar, followed by a brief but instructive discussion on physiological responses to hypoglycemia and on symptomatology. Three classifications on the hypoglycemias are presented, based on glucose turn-over rates, clinical considerations, and etiology. Though undoubtedly complete, none of these classifications add to a better understanding of the underlying disorders. Perhaps a classification based on the disturbance in glucose balance—increased peripheral glucose utilization or loss vs decreased hepatic glucose output from whatever cause—might have permitted a more meaningful discussion of the dynamic etiological production of the various hypoglycemias.


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