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July 11, 1966

Radioisotope Placenta Scanning For Feto-Maternal Abnormalities

JAMA. 1966;197(2):39. doi:10.1001/jama.1966.03110020025013

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Radioisotope scanning for diagnosis of feto-maternal abnormalities such as placenta previa using either technetium 99m or iodine 131 can be performed as early as the fourth or fifth month of pregnancy with diagnostic accuracy of 100% and 97%, respectively, a California research team reports.

"Since, however, technetium 99m (99m Tc) is currently only available for approved experimental purposes, radioactive iodine 131 (131 I) labeled serum albumin is recommended as the most satisfactory and safe isotope for general clinical use," Leon Krohn, MD, told the annual AMA convention.

Dr. Krohn, Henry Jaffe, MD, and Robert Adams compared the effectiveness of both isotopes when used with an automatic scanner and color polaroid attachment which they developed recently.

For the past year or more, 131 I has been used for placental scanning, but with some difficulty due, in part, to the dispersed collimation pattern required by the isotope for adequate visualization.

Although Dr.

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