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July 18, 1966

DMSO—No Human Eye Change Found

JAMA. 1966;197(3):26. doi:10.1001/jama.1966.03110030024011

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There is no evidence so far of the same lens changes occurring in human eyes as were seen in animals treated with dimethyl sulfoxide, a University of Oregon Medical School DMSO investigator told the American Association for the Study of Headache.

Stanley W. Jacob, MD, associate professor of surgery, said that while he has no "inside information," he believes the federal ban on DMSO will be lifted soon.

The suspension of clinical trials of the experimental drug, actually by agreement of the six drug company sponsors, has been in effect for eight months.

"The main reason I believe the ban will be lifted soon," Dr. Jacob told JAMAMedical News, "is that we now have careful pre- and post-treatment evaluations of human eyes after as long as 22 months."

At Cleveland Clinic, which has permission to continue clinical work with DMSO, he told the association, 25 patients with generalized scleroderma

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