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July 25, 1966

Quebec's Medical Mystery Spreads

JAMA. 1966;197(4):27-28. doi:10.1001/jama.1966.03110040015004

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A form of heart disease first reported in Quebec among persons who drank large quantities of beer has been detected in the United States.

At least 40 persons in Omaha, and perhaps three others in Minneapolis, have been shown to have myocardial disease clinically or pathologically similar to that occurring in Quebec.

"It is our belief that this syndrome can be found in other localized centers in North America, and we are anxious to extend the epidemiological study of it," Yves Morin, MD, one of the original investigators in Quebec, told The Journal.

Among the Omaha patients, 16 died; in Minneapolis, one died.

As in Quebec, all of the patients in Omaha and Minneapolis habitually drank large quantities of beer. Among the 48 victims in Quebec (of whom 20 have died), daily beer consumption of from three to seven quarts was not unusual.

When it became apparent that the disease