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August 15, 1966


JAMA. 1966;197(7):23-25. doi:10.1001/jama.1966.03110070011003

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Typhoid Immunization—  The Public Health Service, upon the recommendations of an advisory committee, says there is no need for routine typhoid immunization in this country.The PHS accepted and published the typhoid vaccine recommendations of its Advisory Committee on Immunization Practices:"The incidence of typhoid fever in the United States has declined steadily for many years. At the present time, less than 500 cases are reported annually, and a continuing downward trend can be expected. Cases are sporadic and are primarily related to contact with carriers rather than to common source exposure. Recognizing this epidemiologic pattern of typhoid fever, re-definition of the role and use of typhoid vaccine is indicated."Although typhoid vaccines have been employed for many decades, definitive evidence of their effectiveness has been accumulated only recently from well controlled field investigations. Several different preparations of typhoid vaccine have been shown to afford protection in approximately 70% to