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August 22, 1966

Intensified Bladder Cancer Study Sought

JAMA. 1966;197(8):37. doi:10.1001/jama.1966.03110080025011

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(Continued from page 26) and invasive overt carcinoma."

A colleague from the New York hospital, Harry Grabstald, MD, noted that progression from in situ carcinoma to invasive has been seen in intervals ranging from 8 to 67 months.

Dr. Grabstald, associate attending surgeon, urology service, and also assistant professor in urology, Cornell University Medical College, said radiation therapy may be of value before cystectomy and has been used in treating infiltrating cancer.

Reporting on the cooperative chemotherapy-radiotherapy adjuvants study of which he is chairman, Dr. Prout told the symposium that, while preliminary indications have not been particularly encouraging, no conclusions should be drawn from data to date on studies of 5-fluorouracil's effect on bladder carcinoma and its evaluation as an adjuvant in bladder cancer surgery.

While calculi in the renal pelvis can change epithelial cells into stratified squamous cells, a Greek physician told the symposium, a study in Athens produced