[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.146.176.35. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
August 22, 1966

Systemic Use of Local Anesthetics

Author Affiliations

Philadelphia

JAMA. 1966;197(8):665-666. doi:10.1001/jama.1966.03110080105042

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

To the Editor:—  Dr. John Adriani's otherwise excellent article (196:405, 1966) "Reactions to Local Anesthetics" contains one statement which I consider to be incorrect:The systemic effects of local anesthetics are of very little use clinically. Some physicians use them intravenously, but other drugs are more effective. Thus, there is little justification for using these drugs systemically.Since 1947 we have been using 0.5% or 1% procaine intravenously in combination with thiopental, nitrous oxide, ether, and cyclopropane in various combinations. We find intravenous administration of procaine of value because:

  1. It suppresses respiratory tract secretions so effectively that suction through the endotracheal catheter is almost never necessary.

  2. It suppresses sweat gland secretions so that the skin remains warm and dry and the loss of fluid and electrolytes during surgery is minimized.

  3. It decreases somatic and autonomic sensitivity, so that noxiousreflexes are minimized and the amount

×