A white, 16-year-old girl from New Britain, Conn, had multicentric lymphosarcoma, resembling the childhood lymphoma of Africa (Burkitt tumor). She had a characteristic histologic picture at the onset of her illness with jaw and bilateral ovarian involvement. There was a transient complete response to treatment with cyclophosphamide, but she died six months later, after rapidly progressive disease and bone marrow involvement. This case adds documentation to the existence of Burkitt-like tumors outside of central Africa and demonstrates the unusual finding of a terminal reticulum cell leukemia.
Ziegler JL, Miller DG. Lymphosarcoma Resembling the Burkitt Tumor in a Connecticut Girl. JAMA. 1966;198(10):1071-1073. doi:10.1001/jama.1966.03110230087018