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December 19, 1966

Specific Drugs Urged For CNS Infections

JAMA. 1966;198(12):43. doi:10.1001/jama.1966.03110250025012

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Effective antibiotics are available for combating bacterial infections of the central nervous system. But it's up to the physician to recognize the emergency promptly and treat it specifically.

There is no question that these acute infections represent true medical emergencies. These are particularly dangerous in early infancy, Paul F. Wehrle, MD, told the Congress of Neurological Surgeons in San Juan, Puerto Rico.

Re-evaluation Necessary  "Availability of new and highly effective antibiotics suggests reevaluation of earlier therapeutic routines," he said.Early clinical recognition and prompt laboratory confirmation are essential, he emphasized. But, beyond this, "there is no advantage, and a possible detriment, to using more than a single agent in therapy for the common types of acute bacterial central nervous system infections."Dr. Wehrle, professor of pediatrics at the University of Southern California School of Medicine and chief physician, pediatric and communicable disease services, Los Angeles County General Hospital, noted, however: