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To the Editor:—
A pertinent incident was not mentioned in the editorial about Sir Frederick Banting and the discovery of insulin (198: 660, 1966). In October 1920, Sir Frederick read Dr. Moses Barron's paper describing a fibrotic pancreas wherein the acinar enzyme-secreting cells had disappeared, but the islet cells were intact. That paper, with its references to previous experiments in animals in which almost identical pathologic changes ensued after ligation of the pancreatic duct, incited Banting and Best's experiments in 1921. Details of the event were described in Minnesota Medicine (49:689, 861, 1966) by Dr. Barron, who received the Banting Award from the American Diabetes Association in 1964.
Reimann HA. Moses Barron and Banting. JAMA. 1967;199(1):48. doi:10.1001/jama.1967.03120010092036