[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.166.112.64. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
March 20, 1967

Acanthosis Nigricans And Pituitary Tumors

Author Affiliations

Rochester, Minn

JAMA. 1967;199(12):948. doi:10.1001/jama.1967.03120120136041

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

To the Editor:—  My co-authors and I appreciate Dr. Curth's major contributions to the field of acanthosis nigricans, but we cannot agree entirely with her method of classification. Acanthosis nigricans is a cutaneous manifestation associated with many different conditions, and the prognosis is not associated with the acanthosis nigricans but with the associated disease or mode of inheritance. We do not use the term "pseudoacanthosis nigricans," for histologically and clinically it is in every way similar to acanthosis nigricans. It is not related to obesity, for many of our patients have lost weight without having their acanthosis nigricans involute, and acanthosis nigricans has developed in some patients without obesity. We find it difficult to separate the types II and IV in Dr. Curth's classification, seeing no difference between an inherited acanthosis nigricans which is not associated with congenital dysplasia and one which is associated with phenomena such as congenital lipodystrophy.

×