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April 20, 1963

Carcinoma and Metastases to the Bones of the Hand

Author Affiliations

Washington, D.C.

Associate Director, Tumor Service (Dr. Gold) and Co-director, Rheumatology Service (Dr. Reefe), Georgetown Medical Division, District of Columbia General Hospital, and Clinical Assistant Professor of Medicine (Dr. Gold) and Assistant Professor of Medicine (Dr. Reefe), Department of Medicine, Georgetown University School of Medicine.

JAMA. 1963;184(3):237-239. doi:10.1001/jama.1963.73700160008021a

METASTATIC INVOLVEMENT of the bones of the hand is an infrequent occurrence. Over the past 6 yr in approximately 3,000 patients with various types of malignant disease, only two instances of this type of metastatic involvement have been seen. This geographic location for metastatic disease is usually thought of as an area of late manifestation of widespread skeletal involvement; however, this condition sometimes occurs as an isolated finding and rarely may be the presenting symptom of a visceral carcinoma.1 This report of two patients with metastatic bone lesions of the hand is presented because of the rather unusual locations of the primary tumors, namely the prostate gland and the nasopharyngeal epithelium.

Report of Cases 

Case 1.—  A 76-yr-old male was admitted to the hospital on Feb 12, 1959, because of a 3-week history of fainting spells.Four months prior to admission, the patient noted progressive weakness and anorexia associated with

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