June 15, 1963

Simian MalariaIts Importance to World-Wide Eradication of Malaria

Author Affiliations

Bethesda, Md.

Chief, Laboratory of Parasite Chemotherapy, National Institute of Allergy and Infectious Diseases.

JAMA. 1963;184(11):876-877. doi:10.1001/jama.1963.73700240006011a

UNTIL RECENTLY, it was taken for granted by malariologists that parasites of nonhuman hosts of malaria transmissible to man would not be a problem in the eradication of malaria. This may still be true. The inadvertence was caused by: (1) lack of epidemiological data on such a possibility, and (2) the difficulty experienced by investigators who tried to transmit malaria from lower animals to man.

In May, 1960,1 two members of the staff of our laboratory in Memphis contracted a febrile illness which was diagnosed as malaria of the Plasmodium vivax type. After thorough investigation, the infection was regarded to be of simian origin because: (1) the people were involved in experimental studies of simian malaria, (2) they had carried out large-scale dissections of mosquitoes heavily infected with monkey malaria some 2 weeks before, and (3) neither of the workers had had any contact with human malaria during

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