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August 31, 1963

Transplanted Lung 'Showed Evidence of Function'

JAMA. 1963;185(9):37. doi:10.1001/jama.1963.03060090015006

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"The important thing to be noted is that the transplanted lung did function; the patient's pCO2 returned to near normal within the first 14 hours after surgery," said Dr. George Magovern when discussing the second human lung homotransplantation with The Journal.

Magovern and Dr. Adolph J. Yates were part of the medical group which performed the transplant at Presbyterian-University Hospital in Pittsburgh early in July. The first, done a few weeks earlier at the University of Mississippi Medical Center in Jackson, established the practicality of the operation.

According to the Pittsburgh group, the patient recipient, a 44-year-old male suffering from severe emphysema, exhibited a pCO2 of 105 when he was hospitalized. By the time of operation it was running between 80 and 100; after surgery it had been reduced to 41.

The patient had been hospitalized in a comatose state and an emergency tracheotomy had been performed. Life

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