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This book abounds in personal experiences, and represents the author's views and opinions based on knowledge and observation. He is emphatic in his statement that "except as a result of trauma, arthritis is only a symptom of a disease whose real nidus is in some distant part of the body." Nor would he differentiate synovitis from arthritis, because "only a very short acute inflammation can possibly involve the synovial membrane alone." He also emphasizes the fact that the arthritis may be secondary to a disease in some other part of the body even years after the subsidence of the primary infection. Sepsis and arthritis—this is the sequence of events. Daniel has found that by far the commonest source of arthritis is sepsis in the oral cavity—a fact to which all experienced clinicians now subscribe. As for the toxic arthritis, he suspects a microorganism as being the real cause of the
Arthritis.. JAMA. 1912;LIX(26):2334. doi:10.1001/jama.1912.04270130039023