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May 24, 1890


JAMA. 1890;XIV(21):760. doi:10.1001/jama.1890.02410210024002

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Sugars as Diuretics.  —An interesting communication on this subject is made by Dr. Meilach as the result of experiments performed in the therapeutical laboratory of the Cochin Hospital. Lactose and glucose are the most powerful diuretic sugars. These may be termed renal diuretics; injected in the veins of animals they produce no increase of pressure, and no corresponding alteration of pulse when ingested by man. Diuresis is produced without the appearance of the lactose or glucose in the urine; these substances are consumed in the organism, and thus we have physiological medicaments serving at the same time as food; they possess an advantage over caffeine in producing no nervous derangement. The discharge of urine exceeds the quantity of fluids ingested, the diuresis being produced by a kind of dehydration of the blood. The diuresis reaches its maximum in cases of dropsy, of cardiac or cardio-vascular origin, when the urine contains

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