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March 28, 1903


JAMA. 1903;XL(13):853-854. doi:10.1001/jama.1903.02490130037005

Among the most interesting of the researches on cell toxins is that in which the exciting substance is placental tissue. It is of special interest, first, because there is a possibility that some features of the pathology of pregnancy may be explained by the results obtained, and, second, because the practical use of the serum so obtained seems nearer than is the case of many of the other cytotoxic serums. A reason for this hope lies in the fact that placental tissue is the tissue, par excellence, that can be obtained from human beings in fit condition for use in immunizing animals. With the exception of the blood the placenta is practically the only human substance available for this work. W. Liepmann1 has already made a number of experiments showing that the serum of rabbits immunized with human placenta will produce a precipitate when added to clear human serum

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