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April 18, 1903

Clinical Report.

JAMA. 1903;XL(16):1080-1081. doi:10.1001/jama.1903.02490160032002

SALICYLATE OF SODA IN THE TREATMENT OF BASEDOW'S DISEASE.  CHARLES GILBERT CHADDOCK, M.D.Professor of Diseases of the Nervous System in the Marion-Sims-Beaumont College of Medicine.ST. LOUIS.In the fall of 1900 my attention was called by Dr. J. Babinski of Paris to the treatment of exophthalmic goiter by the administration of salicylate of soda. At that time he saw, in consultation with me, a young man, aged 27, who had developed a goiter during the spring and summer of that year. The tumor presented pulsations like those seen in frankly developed Basedow's disease, but there were no other symptoms proper to that neurosis Additional symptoms consisted of great lassitude, marked mental depression, lack of ambition and interest in intellectual work, and an expressionless countenance quite foreign to the individual. The patient had been treated with iodid of potassium and tincture of iodin externally without effect. On the advice

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