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August 31, 1964

Ammonium Excretion—Medullary Sponge Kidneys

JAMA. 1964;189(9):671. doi:10.1001/jama.1964.03070090021006

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


John H. Felts, MD, and Robert H. Headley, MD, who, with Joseph E. Whitley, MD, and Ernest H. Yount, MD, of Winston-Salem, NC, were authors of an original contribution titled "Medullary Sponge Kidneys: Clinical Appraisal," have written that "A review of data obtained from a series of individuals subjected to short-term ammonium chloride loading revealed an error... in several studies in the calculation of ammonium excretion... [including] Case 2 in our paper [JAMA188:233-36 (April 20), 1964]. Corrected values for ammonium excretion [See last line of table on page 234] are: before loading 33 and 17 μEq per minute; after loading 17, 83, 33, 66, 25, 51, and 66 μEq per minute. A plot of these values against the pH of the respective urine samples shows only one point outside the normal range reported by Wrong and Davies (Quart J Med 28:259-313, 1959).

"Since these are normal rates, the