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John H. Felts, MD, and Robert H. Headley, MD, who, with Joseph E. Whitley, MD, and Ernest H. Yount, MD, of Winston-Salem, NC, were authors of an original contribution titled "Medullary Sponge Kidneys: Clinical Appraisal," have written that "A review of data obtained from a series of individuals subjected to short-term ammonium chloride loading revealed an error... in several studies in the calculation of ammonium excretion... [including] Case 2 in our paper [JAMA188:233-36 (April 20), 1964]. Corrected values for ammonium excretion [See last line of table on page 234] are: before loading 33 and 17 μEq per minute; after loading 17, 83, 33, 66, 25, 51, and 66 μEq per minute. A plot of these values against the pH of the respective urine samples shows only one point outside the normal range reported by Wrong and Davies (Quart J Med 28:259-313, 1959).
"Since these are normal rates, the
Ammonium Excretion—Medullary Sponge Kidneys. JAMA. 1964;189(9):671. doi:10.1001/jama.1964.03070090021006