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March 15, 2000

Omission and Incorrect Color Reproduction

JAMA. 2000;283(11):1427. doi:10.1001/jama.283.11.1427

In the Preliminary Communication entitled "The Relationship Between Cyclooxygenase-2 Expression and Colorectal Cancer" in the October 6, 1999, issue of The Journal (1999;282:1254-1257), Ms Theresa Keane was omitted from the acknowledgment. The authors thank Ms Keane for her technical assistance.

In the same Preliminary Communication, the colors of the 4 photomicrographs in Figure 1 on page 1255 were incorrectly reproduced. The correct image is shown in Figure 1.

Figure 1. Cells Stained for Cyclooxygenase-2 (COX-2)
Image description not available.
A, COX-2 expression in colon cancer epithelial cells; B, COX-2 expression in tumor vascular endothelium and stroma; C, inhibition of COX staining in colon cancer epithelial cells after preabsorption of anti–COX-2 antibody with COX-2 polypeptide; and D, normal colonic epithelium cells. COX-2 staining appears brown. Following antibody incubation, color was developed by immersion of the sections in diaminobenzidine tetrahydrochloride/hydrogen peroxide solution for 2 minutes. Sections were counterstained with hematoxylin (original magnification ×40).