Nurse home visitation prenatally and during the first 2 years after
birth was associated with significant short-term and long-term reductions
in child maltreatment in a previously reported trial conducted among high-risk
families in Elmira, NY. Eckenrode and colleaguesArticle further analyzed long-term
data on child maltreatment in the Elmira trial and found that in families
in which mothers reported having experienced more than 28 incidents of domestic
violence, maltreatment involving the study child was not significantly reduced
in home-visited families compared with families who did not receive home visitation
services. In an editorial, GombyArticle emphasizes that home visitation programs
are unlikely to benefit all families and that recognition of the limitations
of these services is important for targeted implementation and program improvement.
In a cohort of 9454 patients who underwent symptom-limited exercise
electrocardiographic testing and were followed up prospectively for a median
of 5.2 years, Nishime and colleagues found that both abnormal heart rate recovery
and intermediate- or high-risk Duke treadmill exercise scores were predictive
of mortality. Abnormal heart rate recovery provided additional prognostic
information to the treadmill exercise score.
Prostate-specific antigen (PSA) screening for prostate cancer is often
performed annually for men aged 50 through 75 years. Using a Monte-Carlo simulation,
Ross and colleagues compared this standard screening strategy, no screening,
and 6 strategies in which the PSA threshold for prostate biopsy, PSA testing
intervals, and the start age for PSA testing were varied. The strategy of
PSA testing at ages 40 and 45 years followed by biennial testing beginning
at age 50 years, with a PSA threshold of 4.0 ng/mL for prostate biopsy, was
estimated to simultaneously reduce prostate cancer mortality and number of
PSA tests and biopsies performed per 1000 men compared with the standard strategy.
Prior research has suggested a relationship between periodontal disease
and coronary heart disease, but these 2 conditions share common risk factors
and their apparent association may be explained by confounding. In this analysis
of data from 8032 adults aged 25 to 74 years followed up from baseline (1971-1975)
through 1992 in the First National Health and Nutrition Examination Survey
Epidemiologic Follow-up Study, Hujoel and colleagues found no evidence supporting
an association between the presence of periodontitis or gingivitis at baseline
and the risk of coronary heart disease events or mortality.
Limited evidence suggests that computerized reminder systems might improve
physician compliance with specific standards of care. Demakis and colleagues
studied a computerized reminder system in a randomized trial among resident
physicians at 12 Veterans Affairs ambulatory care clinics. In the 17-month
study during which 12,989 patients received care, compliance with applicable
standards of care was significantly greater in the reminder group compared
with the control group. Over time, however, the proportion of visits for which
care was in compliance with the standards declined progressively in the reminder
group, but remained stable in the control group.
"In the sacredness of just being together, . . . none of the struggles
between faith and doubt really mattered anymore." From "Three Lessons."
Pediatric gastroenterologists are pursuing research on probiotic therapy,
in which adding certain microorganisms to the diet can improve microbial functioning
and benefit health.
In this meta-analysis of data from 26 studies, clinical chorioamnionitis
was significantly associated with cerebral palsy in preterm and full-term
infants and with cystic periventricular leukomalacia in preterm infants.
Eight of 22 widely available calcium supplements contain measurable
lead contentArticle, but do these products truly present a health risk?Article
Immediate defibrillation is the optimal treatment for sudden
cardiac arrest due to ventricular fibrillation. EisenbergArticle asserts that defibrillation
should be a lay procedure and argues for widespread dissemination of automated
external defibrillators (AEDS) in homes, whereas Brown and KellermannArticle maintain
that current evidence does not support access to AEDs in public locations
For your patients: Information about maintaining healthy gums.
This Week in JAMA. JAMA. 2000;284(11):1345. doi:10.1001/jama.284.11.1345