[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
Sign In
Individual Sign In
Create an Account
Institutional Sign In
OpenAthens Shibboleth
[Skip to Content Landing]
Citations 0
June 19, 2002

Placebo in Clinical Trials for Depression: Complexity and Necessity—Correction

JAMA. 2002;287(23):3083. doi:10.1001/jama.287.23.3083

Incorrect Wording. There was incorrect wording in the Editorial entitled "Placebo in Clinical Trials for Depression: Complexity and Necessity" published in the April 10, 2002, issue of THE JOURNAL (2002;287:1853-1854). The last 3 sentences in the fourth paragraph should read as follows: From this 8-week clinical trial, the authors conclude that neither sertraline nor hypericum was significantly different from placebo on either of the primary outcome measures: change in total Hamilton Depression Scale (HAM-D) score and full response defined by combined cut-off scores on both the HAM-D and the Clinical Global Impression Scale (CGI-I). However, sertraline was significantly better than placebo (P = .02) on the CGI-I alone, which was a secondary outcome measure in this study. The overall response rates (including partial and full response) were 38.1% for hypericum, 43.1% for placebo, and 48.6% for sertraline.