This Viewpoint discusses the differences between voluntary, involuntary, and nonvoluntary psychiatric treatment.
This Viewpoint discusses the case of Charlie Gard, a young boy with severe mitochondrial disease on life support in the United Kingdom, and the issues at stake in the conflict between his parents’ wishes to pursue expensive, unproven treatment and the UK National Health Service’s insistence on a palliative approach.
This Viewpoint discusses the drug development portfolio—a family of trials assessing a drug for different indications or in different combinations with other drugs—and summarizes some of the challenges drug portfolios pose for policy, care, and human protections.
This cluster randomized trial compares the effects on blood pressure control of a community health worker–led home intervention vs physician education vs patient text messaging among low-income patients with hypertension in Argentina.
This randomized trial compares the effects of postoperative oral cephalexin-metronidazole vs placebo on frequency of surgical site infection (SSI) in obese women undergoing cesarean delivery.
This population epidemiology study uses Medicare administrative data to describe national trends in performance and outcomes of carotid endarterectomy and carotid artery stenting from 1999 to 2014 among fee-for-service Medicare beneficiaries aged 65 years or older.
This randomized clinical trial compares the effect of lorazepam vs placebo added to haloperidol for persistent agitation in patients with advanced cancer and delirium.
This JAMA Clinical Guidelines Synopsis summarizes the 2016 American Psychiatric Association practice guideline on the use of antipsychotics to treat agitation or psychosis in patients with dementia.
A 4-year-old boy had a 1-cm well-circumscribed, symmetrical, pinkish, dome-shaped nodule with central erosions on the left cheek. Hair, nails, and mucosae were of normal appearance, and the remainder of the examination was unremarkable. What would you do next?
A 53-year-old woman with chronic low back pain presented for a prescription refill of hydrocodone/acetaminophen. She had partial paralysis from a thoracic spinal cord infarction secondary to aortic dissection from prior cocaine use and reported taking hydrocodone on that day but no recent illicit drug use. Urine immunoassay drug screen results were negative overall but positive for cocaine. How would you proceed?
This study uses US National Vital Statistics mortality data to assess change in US life expectancy from 2000 to 2015 attributable to opioid-involved poisonings.
Notice of Retraction and Replacement: Favini et al. Comparative Trends in Payment Adjustments Between Safety-Net and Other Hospitals Since the Introduction of the Hospital Readmission Reduction Program and Value-Based Purchasing. JAMA. 2017;317(15):1578-1580.
This Medical News article discusses the importance of correctly prepping patients for blood pressure measurement.
This Arts and Medicine essay uses Kay Redfield Jamison’s 2016 study of poet Robert Lowell to explore writing as a way of calming disintegrated psyches and proposes that physicians collaborate with patients who have bipolar illness to balance the effects medications have on blunting manic symptoms and creative impulses.