Auer and colleagues enrolled 2192 older adults without known cardiovascular disease to determine whether baseline electrocardiographic (ECG) abnormalities or development of new and persistent ECG abnormalities were associated with increased coronary heart disease events. In an editorial, Greenland discusses whether the resting ECG should be ordered as a routine test in healthy asymptomatic adults.
To assess whether losartan use is associated with increased all-cause mortality in heart failure (HF) patients as compared to candesartan, a cohort study by Svanström and coauthors linked individual-level data on hospital contacts, filled prescriptions, and potential confounders in 6479 Danish patients.
Berwick and Hackbarth use a “wedges” model to propose how reducing waste in 6 different categories could bring US health care costs into a sustainable range.
Nishijima and coauthors systematically assess the precision and accuracy of symptoms and tests in identifying intra-abdominal injury in patients with blunt abdominal trauma.