To evaluate the effect of continuous positive airway pressure (CPAP) therapy on the incidence of hypertension or cardiovascular events, Barbé and coauthors randomly allocated 725 nonsleepy patients with obstructive sleep apnea (OSA) to receive CPAP therapy or no active intervention. In the related Editorial, Kapur and Weaver discuss the relationships between OSA and incident hypertension.
Systemic hypertension is prevalent among patients with obstructive sleep apnea (OSA). Continuous positive airway pressure (CPAP) therapy reduces blood pressure in patients with hypertension and OSA. Marin and colleagues determine whether CPAP therapy is associated with a lower risk of incident hypertension. In an editorial, Kapur and Weaver comment on the sleep apnea-hypertension puzzle.
To reduce the prevalence of physical restraints in nursing homes, Köpke and colleagues developed a multicomponent intervention according to an evidence-based guideline and the theory of planned behavior. They tested the intervention in a cluster randomized controlled trial conducted in 2 German cities between February 2009 and April 2010.
Hung and coauthors discuss the case of a patient with hip fracture and the course of his treatment. Randomized controlled trials comparing the efficaciousness of different treatment protocols in patients with hip fracture are assessed.