To determine whether aerobic exercise would improve depressive symptoms and clinical outcomes among patients with heart failure, Blumenthal and coauthors randomly assigned 2322 patients either to participate in aerobic training or to receive education and usual guideline-based care.
Williams and coauthors assess the long-term outcomes of endoscopic vs open vein-graft harvesting for Medicare patients undergoing coronary artery bypass graft (CABG) surgery in the United States. In the related 9079, Dacey discusses whether endoscopic harvesting is safe for CABG surgery.
To determine prevalence of pathogenic APC and MUTYH mutations in patients with multiple colorectal adenomas and compare characteristics of carriers of these mutations, Grover and coauthors conducted a cross-sectional study among 8676 unrelated individuals. Roy provides comments in the related 9516.
Tseng and coauthors studied data from 1 113 640 US Medicare beneficiaries 65 years and older with a diagnosis of cataract between 2002 and 2009 to determine the association of cataract surgery with subsequent fracture risk.
Coburn and coauthors reviewed the literature to help inform clinical decision making about when to order blood cultures in the setting of suspected bacteremia.