In a double-blind placebo-controlled trial of 406 women with threatened preterm labor (26-32 weeks gestation) set in the Netherlands, Roos and colleagues assess the effects of maintenance tocolysis with nifedipine in reducing adverse perinatal outcomes.
In a population-based study of 5 Nordic countries, Stephansson and coauthors analyzed data from more than 1.6 million singleton births to determine whether women who had been treated with a selective serotonin reuptake inhibitor before or during pregnancy were at risk of having stillbirths and whether their infants were at risk of death.
Al-Khatib and coauthors performed a retrospective analysis to determine whether the survival of patients who received an implantable cardioverter-defibrillator (ICD) in primary prevention clinical trials differs from that of trial-eligible patients receiving a primary prevention ICD in clinical practice.
To study neurophysiological factors that might underlie associations between fructose consumption and weight gain, Page and coauthors assigned 20 healthy volunteers to undergo 2 magnetic resonance imaging sessions in conjunction with ingestion of glucose or fructose in a random-order crossover trial. Purnell and Fair provide comment in the related Editorial.
Flegal and coauthors report on the association of all-cause mortality with overweight and obesity using standard body mass index categories. In an accompanying Editorial, Heymsfield and Cefalu discuss whether body mass index adequately conveys a patient’s mortality risk.