To determine whether prenatal exposure to valproate is associated with an increased risk of autism spectrum disorder and childhood autism in offspring, Christensen and coauthors conducted a population-based study of all children born alive in Denmark from 1996 to 2006. Meador and Loring provide comment in the related Editorial.
London and coauthors conducted a retrospective analysis of treatment records to assess the effect of perioperative β-blocker exposure on noncardiac surgical procedures in a population-based sample of 136 745 patients treated at 104 Veterans Health Administration medical centers between 2005 and 2010.
Roed and coauthors conducted a Danish population-based cohort study using national registries to examine educational achievement and economic selfsufficiency in adults who had diagnoses of meningitis as children.
Crochet and coauthors performed a systematic review of 14 studies with 12 101 patients to investigate the accuracy and precision of the patient history, clinical examination, readily available laboratory values, and sonography in the diagnosis of ectopic pregnancy in women with abdominal pain or vaginal bleeding during early pregnancy.