To determine the efficacy of ramipril for improving walking ability, walking performance, and quality of life in patients with peripheral artery disease (PAD) and claudication, Ahimastos and coauthors randomly assigned 212 patients to receive ramipril or placebo for 24 weeks. In the related Editorial, McDermott discusses medications for improving walking performance in PAD.
Coombes and coauthors report on the effect of corticosteroid injection, physiotherapy, or both on clinical outcomes in patients with unilateral lateral epicondylalgia.
Teno and coauthors investigated changes in end-of-life care (site of death, place of care, and health care transitions) for people who died in 2000, 2005, and 2009 via a retrospective study of 848 303 fee-for-service Medicare beneficiaries. In an Editorial, Jenq and Tinetti discuss the importance of eliciting patients’ goals in improving the quality of end-of-life care.
Using the case of a 54-year-old biological male who self-identifies as a woman, Spack reviews management of transgenderism, including mechanisms of gender identity disorder and medical and surgical treatment options for male-to-female and female-to-male transgender individuals.