Prokocimer and coauthors report the results from the ESTABLISH-1 randomized trial of tedizolid phosphate vs linezolid for the treatment of acute bacterial skin and skin structure infections. In an accompanying Editorial, Doron and Boucher discuss new study design and a step toward shorter course therapy of antibiotics for skin infections.
To examine the association between maternal use of prenatal folic acid supplements and subsequent risk of autism spectrum disorders (ASDs) in children, Surén and coauthors assessed 85 175 children from the Norwegian Mother and Child Cohort Study. Berry and coauthors provide comment in the related Editorial.
Morgan and coauthors report the long-term effectiveness of Helicobacter pylori eradication programs for preventing gastric cancer in a randomized trial of 1463 participants in 7 Latin American communities.
Krumholz and coauthors studied Medicare fee-for-service beneficiaries discharged with acute myocardial infarction, heart failure, or pneumonia to determine the relationship between hospital 30-day, all-cause, risk-standardized mortality rates and readmission rates.
In a meta-analysis of data from 7 trials conducted in sub-Saharan Africa, Kayentao and coauthors explored whether 3 or more doses of sulfadoxine-pyrimethamine would be associated with higher birth weight or less risk of low birth weight compared with the standard 2 doses.