Editor's Audio Summary by Howard Bauchner, MD, Editor in Chief of JAMA, the Journal of the American Medical Association, for the April 16, 2014 issue
In a randomized clinical trial involving 241 patients undergoing transcatheter aortic valve replacement, Abdal-Wahab and co-authors found that use of balloon-expandable valves resulted in a greater rate of device success than use of self-expandable valves.
Lincoff and coauthors determine whether addition of aleglitazar to standard medical therapy reduces cardiovascular morbidity and mortality among 7226 patients with type 2 diabetes mellitus (T2D) and a recent acute coronary syndrome (ACS).
Lexis and coauthors conducted a double-blind, placebo-controlled trial in 380 Dutch patients to evaluate the effect of metformin treatment on preservation of left ventricular function in patients without diabetes presenting with ST-segment elevation acute myocardial infarction (AMI).
In an effort to analyze the optimal maternal body mass index for lowering risk of fetal death, stillbirth, and infant death, Aune and colleagues conduct a systematic review and meta-analysis of cohort studies about this topic.
Clauw reviews the epidemiology, pathophysiology, diagnosis, and treatment of fibromyalgia using the case of Ms P, a 64-year-old woman with ongoing diffuse muscle pain and fatigue.