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November 2016 - July 1883

Decade

Year

Issue

January 22, 2014, Vol 311, No. 4, Pages 327-435

In This Issue of JAMA

Highlights

Abstract Full Text
free access has audio
JAMA. 2014;311(4):327-329. doi:10.1001/jama.2013.279290
Viewpoint

The Accelerated Approval of Oncologic DrugsLessons From Ponatinib

Abstract Full Text
JAMA. 2014;311(4):353-354. doi:10.1001/jama.2013.284531

Improving the Drug Development ProcessMore Not Less Randomized Trials

Abstract Full Text
JAMA. 2014;311(4):355-356. doi:10.1001/jama.2013.283742

Care Partners and Online Patient Portals

Abstract Full Text
JAMA. 2014;311(4):357-358. doi:10.1001/jama.2013.285825
A Piece of My Mind

Time to Get Over It

Abstract Full Text
JAMA. 2014;311(4):359-360. doi:10.1001/jama.2013.285398
Editorial

Opening the FDA Black Box

Abstract Full Text
JAMA. 2014;311(4):361-363. doi:10.1001/jama.2013.283946

Will Detection of MicroRNA Biomarkers in Blood Improve the Diagnosis and Survival of Patients With Pancreatic Cancer?

Abstract Full Text
JAMA. 2014;311(4):363-365. doi:10.1001/jama.2013.284665

Evidence-Based Medicine—An Oral History

Abstract Full Text
free access has multimedia
JAMA. 2014;311(4):365-367. doi:10.1001/jama.2013.286182
Original Investigation

Clinical Trial Evidence Supporting FDA Approval of Novel Therapeutic Agents, 2005-2012

Abstract Full Text
free access has multimedia
JAMA. 2014;311(4):368-377. doi:10.1001/jama.2013.282034

Scientific and Regulatory Reasons for Delay and Denial of FDA Approval of Initial Applications for New Drugs, 2000-2012

Abstract Full Text
free access has active quiz
JAMA. 2014;311(4):378-384. doi:10.1001/jama.2013.282542

Sacks and coauthors identify the reasons that US Food and Drug Administration (FDA) marketing approval for new drugs was delayed or denied in drug applications for new molecular entities first submitted to the FDA between 2000 and 2012.

FDA Approval of Cardiac Implantable Electronic Devices via Original and Supplement Premarket Approval Pathways, 1979-2012

Abstract Full Text
free access
JAMA. 2014;311(4):385-391. doi:10.1001/jama.2013.284986

Using the US FDA’s premarket approval (PMA) database, Rome and coauthors analyzed the prevalence and characteristics of changes to cardiac implantable electronic devices made through the PMA supplement process. In an Editorial, Goodman and Redberg discuss how FDA policies of transparency can help balance innovation and protection of public health.

Preliminary Communication

MicroRNA Biomarkers in Whole Blood for Detection of Pancreatic Cancer

Abstract Full Text
free access
JAMA. 2014;311(4):392-404. doi:10.1001/jama.2013.284664

Schultz and coauthors report preliminary data on microRNA biomarkers in whole blood for detection of pancreatic cancer. In an accompanying Editorial, Buchsbaum and Croce discuss whether detection of microRNA biomarkers in blood improve the diagnosis and survival of patients with pancreatic cancer.

Users' Guides to the Medical Literature

How to Use a Subgroup AnalysisUsers’ Guide to the Medical Literature

Abstract Full Text
JAMA. 2014;311(4):405-411. doi:10.1001/jama.2013.285063

Sun and coauthors provide 5 criteria to help clinicians distinguish credible subgroup analyses from spurious subgroup analyses.

JAMA Clinical Challenge

Exercise-Induced Leg Pain and High Blood Pressure

Abstract Full Text
JAMA. 2014;311(4):412-413. doi:10.1001/jama.2013.284646
Research Letter

Association of Mediterranean Diet With Peripheral Artery DiseaseThe PREDIMED Randomized Trial

Abstract Full Text
free access
JAMA. 2014;311(4):415-417. doi:10.1001/jama.2013.280618
Comment & Response

Hormone Therapy Use and Outcomes in the Women’s Health Initiative Trials

Abstract Full Text
JAMA. 2014;311(4):417. doi:10.1001/jama.2013.285154

Hormone Therapy Use and Outcomes in the Women’s Health Initiative Trials—Reply

Abstract Full Text
JAMA. 2014;311(4):417-418. doi:10.1001/jama.2013.285163

Prevention and Control of Hypertension in Different Countries

Abstract Full Text
JAMA. 2014;311(4):418-419. doi:10.1001/jama.2013.285324

Prevention and Control of Hypertension in Different Countries—Reply

Abstract Full Text
JAMA. 2014;311(4):419-420. doi:10.1001/jama.2013.285327

Patient-Reported Outcome Alert Monitoring

Abstract Full Text
JAMA. 2014;311(4):420. doi:10.1001/jama.2013.284321

Patient-Reported Outcome Alert Monitoring—Reply

Abstract Full Text
JAMA. 2014;311(4):420-421. doi:10.1001/jama.2013.284330
Medical News & Perspectives

Public Health Officials Mark 50th Year of Measles VaccineConcern Remains About Outbreaks in Pockets of Unvaccinated

Abstract Full Text
JAMA. 2014;311(4):345-346. doi:10.1001/jama.2013.285502

FDA Moves to Curb Antibiotic Use in Livestock

Abstract Full Text
JAMA. 2014;311(4):347-348. doi:10.1001/jama.2013.285704

Report: States May Be Unprepared to Manage Infectious Disease Threats

Abstract Full Text
JAMA. 2014;311(4):348. doi:10.1001/jama.2013.286094
news@JAMA

From JAMA’s Daily News Site

Abstract Full Text
JAMA. 2014;311(4):348. doi:10.1001/jama.2013.286120
Clinical Trials Update

Gastroesophageal Reflux Symptoms Abate When Smoking Stops

Abstract Full Text
JAMA. 2014;311(4):349. doi:10.1001/jama.2013.286076

Multivitamins Offer No Protection to Brains or Hearts

Abstract Full Text
JAMA. 2014;311(4):349. doi:10.1001/jama.2014.60

Resuming Warfarin After GI Bleeding Leads to Better Outcomes

Abstract Full Text
JAMA. 2014;311(4):349. doi:10.1001/jama.2014.61

Lung Cancers Overdiagnosed With Low-Dose CT

Abstract Full Text
JAMA. 2014;311(4):349. doi:10.1001/jama.2014.62
Health Agencies Update

Pertussis Vaccine May Not Prevent Spread

Abstract Full Text
JAMA. 2014;311(4):350. doi:10.1001/jama.2013.285867

Marijuana, Tobacco Use Associated With Stillbirth Risk

Abstract Full Text
JAMA. 2014;311(4):350. doi:10.1001/jama.2013.286112

Funding to Boost Mental Health Care

Abstract Full Text
JAMA. 2014;311(4):350. doi:10.1001/jama.2013.286116

Less Oversight Needed for Gene Transfer Studies

Abstract Full Text
JAMA. 2014;311(4):350. doi:10.1001/jama.2013.286118
News From the Centers for Disease Control and Prevention

Why Do Parents Decline Vitamin K for Their Newborns?

Abstract Full Text
JAMA. 2014;311(4):351. doi:10.1001/jama.2013.285355

Risks of Nasal Rinsing

Abstract Full Text
JAMA. 2014;311(4):351. doi:10.1001/jama.2013.285359
The Art of JAMA

Portrait of H. H. Thyssen-Bornemisza (Man in a Chair)Lucian Freud

Abstract Full Text
JAMA. 2014;311(4):334-335. doi:10.1001/jama.2013.279292
Poetry and Medicine

Mutually Assured Destruction

Abstract Full Text
JAMA. 2014;311(4):422. doi:10.1001/jama.2013.281574
JAMA Revisited

New Drugs—Miracles or Mirages?

Abstract Full Text
JAMA. 2014;311(4):423. doi:10.1001/jama.2013.279299
JAMA Patient Page

FDA Authorization of Medical Devices

Abstract Full Text
free access
JAMA. 2014;311(4):435. doi:10.1001/jama.2013.286274
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2014;311(4):331-332. doi:10.1001/jama.2013.279291
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