Editor's Audio Summary by Howard Bauchner, MD, Editor in Chief of JAMA, the Journal of the American Medical Association, for the September 17, 2014 issue
This Viewpoint describes the application of the discovery of BRCA1 and discusses screening for BRCA1/2 in clinical practice.
This Viewpoint provides a summary of their discoveries in understanding the role of the basal ganglia in movement, in determining the neurophysiology of Parkinson disease, and in the development of deep brain stimulation.
This follow-up study to a randomized trial determined that antenatal magnesium sulfate was not associated with improved neurological, cognitive, academic, or behavioral outcomes at school age.
Gershon and coauthors conducted a population-based, longitudinal cohort study to estimate the long-term benefits of combination long-acting β-agonists (LABAs) and inhaled corticosteroids compared with LABAs alone among patients with chronic obstructive pulmonary disease. Calverley comments in an Editorial.
This systematic review found that low-molecular-weight heparin combined with vitamin K antagonist did not differ in safety or efficacy from most treatment strategies; however, rivaroxaban and apixaban were associated with the lowest risk of bleeding.
This Clinical Review reports that treatment of hypercholesterolemia for patients at risk for atherosclerotic cardiovascular disease should start before age 80 years.