Editor's Audio Summary by Howard Bauchner, MD, Editor in Chief of JAMA, the Journal of the American Medical Association, for the July 09, 2014 issue
Iranmanesh and colleagues assess surgical treatment options for patients at intermediate risk of a common duct stone in a randomized clinical trial and 6-month follow-up of 100 patients in a Geneva, Switzerland hospital, June 2011-February 2013.
To determine whether antibiotic treatment before and after cholecystectomy, the FRENCH Study group randomized 414 patients between May 2010 and August 2013 with acute calculous cholecystitis to receive either no antibiotic treatment after surgery or amoxicillin plus clavulanic acid for 5 days after surgery. They found that number of infections did not differ between groups.
Koegelenberg and coauthors investigated the efficacy and safety of combining varenicline and a nicotine patch vs varenicline alone in smoking cessation through a randomized, blinded, placebo-controlled clinical trial that included 435 participants from 7 centers in South Africa.
Dvir and coauthors evaluated data from a multinational valve-in-valve implantation registry to determine survival among patients after transcatheter valve-in-valve implantation inside failed surgical bioprosthetic valves.