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February 2017 - July 1883




October 27, 2015, Vol 314, No. 16, Pages 1669-1768

In This Issue of JAMA


Abstract Full Text
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JAMA. 2015;314(16):1669-1671. doi:10.1001/jama.2014.12047

Experience With the Priority Review Voucher Program for Drug Development

Abstract Full Text
JAMA. 2015;314(16):1687-1688. doi:10.1001/jama.2015.11845

This Viewpoint assesses the US Food and Drug Administration’s priority review voucher program to encourage development of drugs to treat neglected tropical diseases or rare pediatric disease and recommends improvements to the program.

Time for a More Unified Approach to Pediatric Health Care Policy?The Case of Congenital Heart Care

Abstract Full Text
JAMA. 2015;314(16):1689-1690. doi:10.1001/jama.2015.10166

This Viewpoint argues for regionalization of care and accompanying payment reform to improve quality and reduce the costs of caring for children with complex health care needs.

Bridging Unmet Medical Device Ecosystem Needs With Strategically Coordinated Registries Networks

Abstract Full Text
JAMA. 2015;314(16):1691-1692. doi:10.1001/jama.2015.11036

This Viewpoint proposes implementation of strategic coordinated registries networks as the foundation for a national surveillance system that inform decisions about medical device safety, effectiveness, and quality.

A Piece of My Mind

A Piece of My Mind—Actually

Abstract Full Text
JAMA. 2015;314(16):1693-1694. doi:10.1001/jama.2015.8429

Assessing Toxicity of Intravenous Crystalloids in Critically Ill Patients

Abstract Full Text
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JAMA. 2015;314(16):1695-1697. doi:10.1001/jama.2015.12390

The Changing Landscape of Noninvasive Ventilation in the Intensive Care Unit

Abstract Full Text
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JAMA. 2015;314(16):1697-1699. doi:10.1001/jama.2015.12401

Mortality Trends and Signs of Health Progress in the United StatesImproving Understanding and Action

Abstract Full Text
JAMA. 2015;314(16):1699-1700. doi:10.1001/jama.2015.12391
Original Investigation

Effect of a Buffered Crystalloid Solution vs Saline on Acute Kidney Injury Among Patients in the Intensive Care UnitThe SPLIT Randomized Clinical Trial

Abstract Full Text
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JAMA. 2015;314(16):1701-1710. doi:10.1001/jama.2015.12334

This randomized trial determines the effect of a buffered crystalloid compared with saline on renal complications among patients in the intensive care unit.

Effect of Noninvasive Ventilation vs Oxygen Therapy on Mortality Among Immunocompromised Patients With Acute Respiratory FailureA Randomized Clinical Trial

Abstract Full Text
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JAMA. 2015;314(16):1711-1719. doi:10.1001/jama.2015.12402

This randomized trial compares the effects of noninvasive ventilation vs oxygen alone on 28-day mortality among immunocompromised patients with acute hypoxemic respiratory failure.

Anticholinergic vs Long-Acting β-Agonist in Combination With Inhaled Corticosteroids in Black Adults With AsthmaThe BELT Randomized Clinical Trial

Abstract Full Text
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JAMA. 2015;314(16):1720-1730. doi:10.1001/jama.2015.13277

This randomized trial compares the effectiveness and safety of tiotropium vs long-acting β-agonists among black adults with asthma using inhaled corticosteroids, and determines whether polymorphisms at a locus of the β2-adrenergic receptor gene affect treatment response.

Temporal Trends in Mortality in the United States, 1969-2013

Abstract Full Text
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JAMA. 2015;314(16):1731-1739. doi:10.1001/jama.2015.12319

This population epidemiology study uses US National Vital Statistics System data to characterize trends in all-cause and cause-specific mortality between 1969-2013.

JAMA Clinical Challenge

Widespread Scaly Eruption in a Patient With Multiple Comorbidities

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JAMA. 2015;314(16):1740-1741. doi:10.1001/jama.2015.9391

A 73-year-old woman presented with a widespread scaly pruritic rash lasting 2 months. She had an antinuclear antibody titer of 1:80, elevated SS-A antibodies, a creatinine level of 1.8 mg/dL, and an inflammatory pattern on skin biopsy. What would you do next?

JAMA Diagnostic Test Interpretation


Abstract Full Text
JAMA. 2015;314(16):1742-1743. doi:10.1001/jama.2015.7871

A 47-year-old man presents with bitemporal visual field defects, low libido, and an elevated prolactin level. How do you interpret the test results?

From The Medical Letter on Drugs and Therapeutics

Abuse-Deterrent Opioid Formulations

Abstract Full Text
JAMA. 2015;314(16):1744-1745. doi:10.1001/jama.2015.12869

This Medical Letter review summarizes several opioid formulations that claim to deter abuse.

Research Letter

Adequacy of Outpatient Specialty Care Access in Marketplace Plans Under the Affordable Care Act

Abstract Full Text
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JAMA. 2015;314(16):1749-1750. doi:10.1001/jama.2015.9375

This study examines access to specialists in US physician networks participating in the Affordable Care Act’s insurance marketplaces in 2015.

Comment & Response

Medical Use of Cannabinoids

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JAMA. 2015;314(16):1750-1751. doi:10.1001/jama.2015.11429

Medical Use of Cannabinoids

Abstract Full Text
JAMA. 2015;314(16):1751. doi:10.1001/jama.2015.11435

Medical Use of Cannabinoids—Reply

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JAMA. 2015;314(16):1751-1752. doi:10.1001/jama.2015.11447

Promise of Precision Medicine

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JAMA. 2015;314(16):1752. doi:10.1001/jama.2015.11191

Promise of Precision Medicine—Reply

Abstract Full Text
JAMA. 2015;314(16):1752. doi:10.1001/jama.2015.11197

Clarification of Author Affiliation

Abstract Full Text
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JAMA. 2015;314(16):1753. doi:10.1001/jama.2015.12980

Errors in the Tables

Abstract Full Text
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JAMA. 2015;314(16):1753. doi:10.1001/jama.2015.12988
Medical News & Perspectives

Working Late, Courting Stroke

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JAMA. 2015;314(16):1679-1680. doi:10.1001/jama.2015.12245

This Medical News & Perspectives article describes the stroke risk associated with working too many hours and efforts to protect workers’ health as well as promote wellness.

The JAMA Forum

Seeking Rational Approaches to Fixing Hospital Readmissions

Abstract Full Text
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JAMA. 2015;314(16):1681-1682. doi:10.1001/jama.2015.13254
Clinical Trials Update

Benznidazole Does Not Affect Chagas Cardiomyopathy

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JAMA. 2015;314(16):1684. doi:10.1001/jama.2015.12704

PrEP Reduces Incidence of HIV in Clinical Settings

Abstract Full Text
JAMA. 2015;314(16):1684. doi:10.1001/jama.2015.13424

No Benefit From High 25(OH)D Levels for Postmenopausal Women

Abstract Full Text
JAMA. 2015;314(16):1684. doi:10.1001/jama.2015.13426
Health Agencies Update

Medicare ACOs Improving Quality of Care: CMS Report

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JAMA. 2015;314(16):1683. doi:10.1001/jama.2015.12840

NIH Awards $35 Million in Natural Products Research Grants

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JAMA. 2015;314(16):1683. doi:10.1001/jama.2015.13579

Proposed Rules for Improving Health Care Access and Equity

Abstract Full Text
JAMA. 2015;314(16):1683. doi:10.1001/jama.2015.13581
News From the Centers for Disease Control and Prevention

Nursing Homes Need Improved Antibiotic Stewardship

Abstract Full Text
JAMA. 2015;314(16):1685. doi:10.1001/jama.2015.13264

Meeting Children’s Needs During Public Health Emergencies

Abstract Full Text
JAMA. 2015;314(16):1685. doi:10.1001/jama.2015.13335
The Art of JAMA

Evening (Landscape in Brilliant Colors)Nikolai Nedashkovsky

Abstract Full Text
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JAMA. 2015;314(16):1676-1677. doi:10.1001/jama.2014.12049
Poetry and Medicine


Abstract Full Text
JAMA. 2015;314(16):1755. doi:10.1001/jama.2015.6421
JAMA Revisited

The Cleveland Museum of Health

Abstract Full Text
JAMA. 2015;314(16):1761. doi:10.1001/jama.2014.12056
JAMA Patient Page

Distracted Driving

Abstract Full Text
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JAMA. 2015;314(16):1768. doi:10.1001/jama.2015.13350
JAMA Masthead


Abstract Full Text
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JAMA. 2015;314(16):1673-1674. doi:10.1001/jama.2014.12048