In this Viewpoint, Thomas Insel discusses the possibility that sensor, keyboard, and voice and speech data from smartphones might be used as a digital phenotype to improve patient-specific measurement-based behavioral care.
This Viewpoint reviews recent research findings questioning the status of cognitive behavioral therapy as the gold standard for treating mental disorders.
This Viewpoint describes trends in the use of conversational artificial intelligence in mental health care and discusses potential advantages and risks to patients and the public.
This Viewpoint uses FDA approval of tisagenlecleucel, the first chimeric antigen receptor T-cell (CAR-T) agent approved for human use, to discuss escalating drug prices for oncology therapies and the complex considerations of outcomes and value that should justify the pricing.
This Medical News story discusses 2 new toolkits aimed at helping primary care physicians detect, diagnose, and manage dementia in patients.
This Viewpoint urges the use of clinical judgment and evidence-based standards when evaluating or testifying about child abuse injuries in light of a rise in unsubstantiated theories (such as vitamin D deficiency) that discount abuse as a cause of those injuries.
In this Viewpoint, Walter Willett and colleagues discuss the methodological challenges of conducting meta-analyses of observational nutrition studies and propose a set of standards to reduce confusion about conflicting recommendations from nutrition reviews that come to different conclusions.
This Viewpoint discusses the potential risks of the US Food and Drug Administration’s 2016 approval of the Dexcom G5 Mobile continuous glucose monitor for making diabetes treatment decisions without confirmation of the device’s readings with fingerstick or laboratory testing.
This Medical News article discusses current efforts and obstacles in developing male contraceptives.
This cohort study compares estimates of sepsis incidence, outcomes, and trends based on clinical data from US hospital electronic health record systems vs claims-based ICD-9 data.
This JAMA Clinical Guidelines Synopsis summarizes the 2017 Endocrine Society clinical practice guideline on endocrine treatment of gender-dysphoric/gender-incongruent persons.
This Viewpoint discusses the immediate and long-term consequences of Hurricane Harvey including impact on mental and physical health of the affected population.
This study characterizes discrepancies between primary outcomes specified in trial protocols, registrations, and publications, and the association between prospective registration and consistency of published outcomes.
This Viewpoint reviews the development of immune checkpoint inhibitors as a new drug class for treating cancer, and discusses future directions including development of commercial assays for identifying response-to-treatment biomarkers and the use of combination regimens to improve response.
This Viewpoint discusses a new FDA regulatory plan to reduce the burden of smoking-related disease by requiring reduction of nicotine in combustible tobacco products beneath addicting levels and by encouraging innovations in novel reduced-risk nicotine products.
This Medical News article discusses recent advances and challenges in the development of liquid biopsies for cancer management.
This Viewpoint notes that nutrition and health behavior change should become a core competency for all physicians and other health professionals working with patients at risk for nutrition-related chronic disease.
This Viewpoint discusses the importance of research authorship for academic promotion and proposes revision of research integrity codes to define nonauthor contributions and distinguish nonauthor from author contributions to discourage awarding of authorship to nonauthor collaborators.