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Research Letter
February 2017

Left Ventricular Dysfunction and Conduction Disturbances in Patients With Myotonic Muscular Dystrophy Type I and II

Author Affiliations
  • 1Section for Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
  • 2Center of Genetic Muscle Disorders, Johns Hopkins University School of Medicine, Baltimore, Maryland
  • 3Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland
  • 4Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland
  • 5Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland
  • 6Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
  • 7Section for Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia
JAMA Cardiol. 2017;2(2):225-228. doi:10.1001/jamacardio.2016.4145

Electrocardiographic (ECG) abnormalities and left ventricular (LV) dysfunction are associated with mortality in type I and type II myotonic muscular dystrophy (MMD).13 We sought to quantitate the baseline prevalence and longitudinal incidence of conduction abnormalities and LV dysfunction during intermediate-term follow-up of a cohort of patients with MMD.

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